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JACOB
BRONSTEIN

WELCOME

I Produce Media, Build Software, and Run Operations

I combine video production, technology, and workflow design to help teams communicate, collaborate, and execute better across clinical research, biotech, software, and media.

CLIENTS

Solving Complexity at Scale

Biotech & Clinical Research

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Supporting sponsors, CROs, and research sites across multiple therapeutic areas.

Clinical Trials

50+
430%

Enrollment Growth

Operational redesign during a Phase 2 oncology study.

Confidential

Pharmaceutical Programs

Supported multiple top tier global pharmaceutical and biotech sponsors across Phase 1 through Phase 3 clinical trials under confidential engagements.

By streamlining and accelerating participant enrollment.

$30M+

Operational Costs Saved

Technology & Education

Scaled educational platforms from prototype to commercial products.

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$2M

Platform User Revenue Growth

Measured through product redesign and user feedback.

240%

Increase in User Engagement

Educational content designed for teachers, clinicians, and students.

1,000+

Books, Videos & Learning Activities Created

Media & Entertainment

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Production Cost Reduction

Production workflow redesign.

91%

Trainning, marketing and commercial media

2,500+

Hours of Professional video content

Unlocked new revenue streams  through product and workflow innovation.

$20M+

Additional Client Revenue Generated

I've helped organizations ranging from startups to global industry leaders solve complex operational challenges through better systems, software, training, communication, and AI.

Different challenges require different solutions. I adapt the people, processes, technology, and tools around what projects actually need.

CASE STUDIES

Uniquely Designed Approaches

CLINICAL RESEARCH

Improving Patient Recruitment

The Problem

Clinical trials often struggle with enrollment, startup delays, and inconsistent site execution long before the visible problem becomes obvious.

In Practice

This approach has been applied across more than 50 clinical trials and multiple therapeutic areas.

Our Observations

The biggest bottlenecks are often a collection of small hidden workflows changeless  that researchers, sites, and participants are expected to navigate.

Best Results to Date

430%

Enrollment Growth

Our Solution

Map the study, identify the hidden friction with teams, test the assumptions with sites, and finally update the workflows and comm. materials.

Operational Cost Savings

$30M+

BIOTECH & BIOLOGIC MANUFACTURING

Increasing Therapeutic Protein Production

The Problem

Biologic medicines are expensive to manufacture because mammalian cells produce limited amounts of therapeutic protein, increasing costs and limiting scalability and patient access.

In Practice

Most information is confidential, but the technology has advanced into real-world applications through our work with  Janssen,  Johnson & Johnson Innovation, and BARDA across biologics and gene therapy products.

A novel cell engineering platform designed to create higher performing mammalian cell lines capable of producing significantly more therapeutic protein while maintaining product quality and consistency.

Our Solution

The Outcome

Higher yielding cells allow manufacturers to produce more medicine using existing facilities, equipment, and production infrastructure, reducing cost while improving scalability.

Results

Up to

90%

Lower manufacturing costs

DIGITAL COMMUNICATIONS & MEDIA PRODUCTION SYSTEMS

Building Global Remote Production Systems

The Problem

Traditional video production is expensive, slow, and difficult to scale, especially when teams, specialists, and projects are distributed across locations.

In Practice

Built and deployed 5 iterations across multiple companies, consistently delivering faster production, lower costs, and more scalable global workflows.

My Solution

Instead of pulling everything down from the cloud, we use the cloud to synchronize work happening at the edge, allowing teams to use the best local prosumer tools while collaborating globally.

Best Results to Date

63%

Faster production timelines

How it Scales

Rapidly deploy global production systems by connecting existing cloud services and low cost tools, enabling synchronized workflows, seamless handoffs, and 24/7 production across time zones.

$1,200 to $103

Cost Per Finished Minute

ABOUT ME

Outside of Work

After living in New York City, the San Francisco Bay Area, and New Orleans, I moved to Richmond, Virginia, with my wife, daughter, son, and dog. 

 

My favorite activities are biking, hiking, canoeing, jumping into oceans and rivers that are far too cold, and discussing the details of the universe over coffee.

CONTACT

Let’s Work Together

Have a complex problem, an ambitious project, or just an idea worth exploring? Send me a message and let’s talk

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